How skipping meals, dining out fuel obesity, exposure to harmful chemicals

*Foods consumed at restaurants, fast food outlets associated with higher levels of phthalates
New research warns that dieting and skipping meals can do more harm than good to your waistline.

While millions jump on the diet wagon every year, a study shows severely limiting calorie intake can wreck havoc on metabolism.

Detoxes also tend to lead to overeating, they found, suggesting there are more downsides than benefits to dieting in both the short term and the long term.

The study’s authors, at the University of Helsinki, conclude that eating meals regularly is the best way to ensure a healthy weight, and making it easier to control your weight in later life.

The study was published in the international Eating Behaviors journal.

Researchers, led by nutritional therapist, Ulla Kärkkäinen, collected data from more than 4,900 young men and women. The participants answered surveys mapping out factors impacting weight and weight change when they were 24 years of age, and again ten years later at the age of 34.

They found that most participants gained weight during the decade-long study, while only 7.5 percent of women and 3.8 percent of men lost weight.

Over the 10 years the average weight gain in women was just under two pounds per year and in men, 2.2 pounds (0.99kg).

Kärkkäinen and her colleagues said one of the common factors among young women and men who succeeded in managing their weight in the long term was eating food regularly as opposed to dieting.

“Often, people try to prevent and manage excess weight and obesity by dieting and skipping meals. In the long term, such approaches seem to actually accelerate getting fatter, rather than prevent it,’ Kärkkäinen said.

Also, another study found that dining out more at restaurants, cafeterias and fast-food outlets might boost total levels of potentially health-harming chemicals called phthalates in the body.

Phthalates, a group of chemicals used in food packaging and processing materials, are known to disrupt hormones in humans and are linked to a long list of health problems.

The study is the first to compare phthalate exposures in people who reported dining out to those more likely to enjoy home-cooked meals. People who reported consuming more restaurant, fast food and cafeteria meals had phthalate levels that were nearly 35 percent higher than people who reported eating food mostly purchased at the grocery store, according to the study.

“This study suggests food prepared at home is less likely to contain high levels of phthalates, chemicals linked to fertility problems, pregnancy complications and other health issues,” says senior author Ami Zota, ScD, MS, an assistant professor of environmental and occupational health at Milken Institute School of Public Health (Milken Institute SPH) at the George Washington University. “Our findings suggest that dining out may be an important, and previously under-recognized source of exposure to phthalates for the U.S. population.”

Lead author Julia Varshavsky, PhD, MPH, at the University of California, Berkeley, School of Public Health, Zota, and their colleagues used data from the National Health and Nutrition Examination Survey (NHANES) collected between 2005 and 2014. The 10,253 participants in the study were asked to recall what they ate and where their food came from in the previous 24 hours.

The researchers then analyzed the links between what people ate and the levels of phthalate break-down products found in each participant’s urine sample. The team found that 61 percent of the participants reported dining out the previous day. In addition, the researchers found:

*The association between phthalate exposure and dining out was significant for all age groups but the magnitude of association was highest for teenagers;

*Adolescents who were high consumers of fast food and other food purchased outside the home had 55 percent higher levels of phthalates compared to those who only consumed food at home;

*Certain foods, and especially cheeseburgers and other sandwiches, were associated with increased levels of phthalates–but only if they were purchased at a fast-food outlet, restaurant or cafeteria. The study found that sandwiches consumed at fast food outlets, restaurants or cafeterias were associated with 30 percent higher phthalate levels in all age groups.

“Pregnant women, children and teens are more vulnerable to the toxic effects of hormone-disrupting chemicals, so it’s important to find ways to limit their exposures,” says Varshavsky, who is also a postdoctoral scientist at the University of California, San Francisco. “Future studies should investigate the most effective interventions to remove phthalates from the food supply.”

Meanwhile, the first study is not the first to show this link between skipping meals, dieting and obesity.

Research published in a 2015 issue of The Journal of Nutritional Biochemistry found that skipping meals not only leads to weight gain, it can increase the risk of insulin resistance and type 2 diabetes.

A similar study published in 2013 by the Oregon Research Institute found that limiting calorie intake increases the risk of weight gain by making unhealthy food more attractive.

The current study concludes that the cornerstone of successful weight management is refraining from dieting and observing regular eating habits, in both women and men.

“Generally speaking, weight management guidance often boils down to eating less and exercising more. In practice, people are encouraged to lose weight, whereas the results of our extensive population study indicate that losing weight is not an effective weight management method in the long run,” said Kärkkäinen.

The findings prove that instead of losing weight, it is more important to focus on eating regular meals, taking care of one’s wellbeing and finding a more general sense of meaning in life.

Regular and sufficient meals support the natural biological functions of the body, and help in managing one’s eating habits and weight management in the long term.

“Our findings demonstrate that weight management would benefit from an increased focus on individual differences, as well as perceiving the factors that impact human wellbeing and the sense of meaning in life as a broader whole,” Kärkkäinen sums up.

A previous study by Zota and colleagues suggested that fast food might expose consumers to higher levels of phthalates. That study found that people who ate the most fast food, burgers, fries and other foods, had phthalate levels that were as much as 40 percent higher than people who rarely ate such foods

The new study looked more broadly at dining out–not just at fast-food outlets–and found that it was significantly associated with increased exposure to phthalates. The authors say the findings are worrisome because two-thirds of the U.S. population eats at least some food outside the home daily.

Additional authors of the study include Rachel Morello-Frosch at the University of California, Berkeley, and Tracey Woodruff at the University of California, San Francisco.

The team used an innovative method of assessing real-world exposures to multiple phthalates, called cumulative phthalate exposure, which takes into account evidence that some phthalates are more toxic than others. The National Academies of Sciences has weighed in twice on phthalates–first in a 2008 report, they recommended using cumulative risk assessments in order to estimate the human health risk posed by this class of chemicals; and then in 2017 with a report finding that certain phthalates are presumed to be reproductive hazards to humans.

Many products contain phthalates, including take-home boxes, gloves used in handling food, food processing equipment and other items used in the production of restaurant, cafeteria and fast food meals. Previous research suggests these chemicals can leach from plastic containers or wrapping into food.

If verified by additional research, the findings from this study suggest that people who love dining out are getting a side of phthalates with their entrée.

Home-cooked meals may be one way to limit exposure to these harmful chemicals. “Preparing food at home may represent a win-win for consumers,” adds Zota. “Home cooked meals can be a good way to reduce sugar, unhealthy fats and salt. And this study suggests it may not have as many harmful phthalates as a restaurant meal.”

At the same time, phthalate contamination of the food supply also represents a larger public health problem, one that must be addressed by policymakers. Zota and Woodruff’s previous research shows that policy actions, such as bans, can help reduce human exposure to harmful phthalates.