Health Innovation: Godson Ndubueze’s PrEPscriber redefines HIV/STI prevention

As the world commemorates World AIDS Day 2024, the theme “Collective Action: Sustain and Accelerate HIV Progress” rings louder than ever, calling on health leaders, communities, and innovators to confront the unfinished fight against HIV with urgency, creativity, and inclusion.

One of those answering that call is Dr. Godson Ndubueze, a physician, infectious disease expert, and public health innovator who is transforming how HIV prevention is delivered and discussed, locally and globally.

In a world where over a million people contract a sexually transmitted infection (STI) each day and HIV continues to disproportionately affect sub-Saharan Africa and underserved populations in the U.S., Dr. Ndubueze is pioneering a digital movement that merges clinical expertise, data, and empathy to close the prevention gap.

He is the founder of PrEPscriber, a global digital platform advancing access to Pre-Exposure Prophylaxis (PrEP) and promoting sexual health literacy. At the heart of this work lies a clear conviction: Access to prevention is a right, not a privilege.
“For too long, HIV prevention has been the afterthought of health systems—fragmented, stigmatised, and inaccessible,” says Dr. Ndubueze. “PrEPscriber is our response: a bridge between communities, education, and services.”

Dr. Ndubueze’s approach is grounded in years of frontline work leading HIV programs supported by PEPFAR and the CDC in Nigeria. As a former State Clinical Mentor, he restructured patient retention systems and witnessed firsthand how even the best treatments fail when prevention is left behind.

That experience shaped PrEPscriber into more than a digital locator, it’s a global ecosystem preparing for pilot launches in both Nigeria and the United States. It targets high-risk populations and aims to transform how people find and access HIV prevention services, particularly PrEP.

PrEPscriber’s debut project is PHASE 1.0: Hey Sammie—a 24/7 interactive hotline and digital resource for users to confidentially ask questions about PrEP, STIs, consent, and sexual health. Designed using the CARE Model (Connect, Assess, Respond, Empower), it creates a safe space for dialogue, not just information.

“Hey Sammie is designed for the young woman in Lagos who’s too afraid to ask her doctor about PrEP, or the teenager in Atlanta unsure what consent really means,” says Dr. Ndubueze. “It’s about creating digital sanctuaries where silence is broken and knowledge leads to action.”

The tool uses culturally adapted AI scripts and live human support to engage youth, LGBTQ+ individuals, and people in conservative or rural communities—audiences often left behind in traditional outreach efforts.

Beyond Hey Sammie, PrEPscriber is developing a global PrEP locator using GIS mapping and pharmacy partnerships to embed prevention access into the fabric of daily life. In Nigeria, where pharmacists are often the first point of care, the model empowers them to become confidential access points for PrEP. In the U.S., the platform will partner with community clinics and telehealth providers to reach Black and Latino populations disproportionately affected by HIV.

What makes PrEPscriber stand out is its fusion of behavioral science, human-centered design, and advocacy. It isn’t just plugging holes in a system—it’s rewriting the script for HIV prevention.

To amplify its reach, Dr. Ndubueze is collaborating with Amarachi Ijeoma, a leading sexual health advocate and YouTube creator with over 250,000 subscribers and 11 million views. Together, they are co-creating content that’s not only medically accurate, but also culturally resonant and emotionally engaging.

“Amarachi brings health to life for young people,” Dr. Ndubueze says. “By blending storytelling with evidence-based messaging, we’re reaching people where they are on their phones, in their language, in formats they trust.”

Their content focuses on high-impact themes including PrEP awareness, STI prevention, cervical cancer screening, and relationship safety, making health education both viral and vital.

As PrEPscriber and Hey Sammie gear up for their pilot phase in 2025, Dr. Ndubueze is also working to shape long-term change by advocating for: Inclusion of PrEP in Nigeria’s national health insurance scheme; Expanded prescribing authority for pharmacists and nurses; Integration of sexual health education in school curricula
“Technology is just the beginning,” he reflects. “Real change comes when tools, policy, and people work together to build systems that are equitable, inclusive, and unstoppable.”

On this World AIDS Day, Dr. Godson Ndubueze’s story exemplifies the theme in action. Through PrEPscriber, Hey Sammie, and strategic collaborations, he’s not just contributing to the global response, he’s helping to lead it.

As we look ahead, his work reminds us that progress doesn’t happen in isolation. It’s powered by voices, vision, and collective action, the kind that sustains momentum and accelerates the end of HIV, once and for all

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