B
The Spaniard misses the Liga clash at the Camp Nou with “a right quadriceps strain” his club said.
“No date has been scheduled for a return as yet,” their statement added.
Roberto suffered multiple injuries last season, missing a total of 37 matches.
And his build-up to the 2021/22 campaign was hindered by a two-week absence after injury to his ribs.
Barca B coach Sergi Barjuan takes charge at Camp Nou after Koeman’s sacking on Wednesday following a 1-0 defeat by Rayo Vallecano at Vallecas.
Two wins in seven league games have left Barca languishing in ninth, nine points adrift of leaders Real Sociedad.