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Very low birth weight ‘may increase risk of later-life psychiatric problems’

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BABIES with a very low birth weight may be at much higher risk of depression, ADHD or other psychiatric conditions in adulthood, compared with those born a healthy weight, and steroid use just before birth may increase this risk even further. This is according to a new study published in the journal Pediatrics.

     Study participants with an extremely low birth weight were 4.5 times more likely to develop psychiatric disorders.

      But it is not all bad news for very low-birth-weight babies; the research team – led by Dr. Ryan Van Lieshout, professor of psychiatry and neurosciences in the Michael G. DeGroote School of Medicine at McMaster University in Canada – also found they are at lower risk of alcohol or substance abuse.

    According to the Centers for Disease Control and Prevention (CDC), around 8% of babies in the US were born a low birth weight (less than 2,500 g) in 2013, while around 1.4 per cent of babies were born a very low birth weight (less than 1,500 g).

    The most common driver behind low birth weight is premature birth; approximately 7 in 10 low-birth-weight babies in the US are born preterm. Other causes include fetal growth restriction and infection during pregnancy.

    Past studies have established that babies with a low birth weight are at increased risk of numerous health problems later in life, including obesity, hypertension, diabetes and heart disease. But how does low birth weight affect mental health in adulthood?

Very low-birth-weight babies up to 4.5 times higher risk of psychiatric problems

    To find out, Dr. Van Lieshout and his team analyzed the presence of psychiatric disorders among 84 adults who were born an extremely low birth weight (less than 1,000 g) and 90 adults who were born a normal birth weight.

    All participants were born between 1977 and 1982 in Ontario, Canada, and were in their early 30s at the time of assessment.

    The researchers found that the participants with an extremely low birth weight were three times less likely to develop a substance or alcohol use disorder than those with a normal birth weight.


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