
Thiago replaced James Milner in an otherwise unchanged starting side from the team for the 3-1 loss at Leicester at the weekend which left Liverpool 13 points behind leaders Manchester City in the Premier League.
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Leipzig coach Julian Nagelsmann started with Spain’s Dani Olmo, with playmaker Emil Forsberg sidelined by a knee injury.
France defender Dayot Upamecano started at centre-back after it was confirmed at the weekend that he will join Bayern Munich next season.
The first-leg tie was moved from Leipzig to Budapest due to Germany’s strict Covid-19 travel restrictions, with the return leg at Anfield scheduled for March 10.
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Starting line-ups (2000 GMT kick-off)
RB Leipzig (3-4-2-1)
Peter Gulacsi; Lukas Klostermann, Dayot Upamecano, Nordi Mukiele; Marcel Sabitzer (c), Kevin Kampl, Tyler Adams, Angelino; Amadou Haidara, Dani Olmo; Christopher Nkunku
Coach: Julian Nagelsmann (GER)
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Liverpool (4-3-3)
Alisson Becker; Trent Alexander-Arnold, Ozan Kabak, Jordan Henderson (c), Andy Robertson; Thiago Alcantara, Georginio Wijnaldum, Curtis Jones; Mohamed Salah, Roberto Firmino, Sadio Mane
Coach: Jurgen Klopp (GER)
Referee: Slavko Vincic (SVN)
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