Adrien Rabiot starts in the Juventus midfield in their Champions League last-16 first leg against Lyon in his native France on Wednesday, as both Aaron Ramsey and Blaise Matuidi are left on the bench at kick-off.
Cristiano Ronaldo is joined in the Italian champions’ attack by Juan Cuadrado and Paulo Dybala, with Gonzalo Higuain a substitute.
Ronaldo, who recently turned 35, has scored in each of his nine appearances for Juve in 2020 and has netted 19 goals since the beginning of December.
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Meanwhile, Lyon coach Rudi Garcia has handed a Champions League debut to Brazilian midfielder Bruno Guimaraes, a January signing from Athletico Paranaense.
French international Leo Dubois will also play at right-back in a 3-5-2 formation having recovered from injury.
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Juventus are heavy favourites to beat a Lyon side struggling in seventh place in France’s top flight and who are without their star player and captain, Memphis Depay, due to a long-term knee injury.
Lyon (3-5-2)
Anthony Lopes; Jason Denayer (capt), Marcelo, Fernando Marcal; Leo Dubois, Bruno Guimaraes, Lucas Tousart, Houssem Aouar, Maxwel Cornet; Karl Toko-Ekambi, Moussa Dembele
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Coach: Rudi Garcia (FRA)
Juventus (4-3-3)
Wojciech Szczesny; Danilo, Leonardo Bonucci (capt), Matthijs de Ligt, Alex Sandro; Rodrigo Bentancur, Miralem Pjanic, Adrien Rabiot; Juan Cuadrado, Paulo Dybala, Cristiano Ronaldo
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Coach: Maurizio Sarri (ITA)
Referee: Jesus Gil Manzano (ESP)
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